Preheat the oven to 375°F. Line two baking sheets with parchment paper.
In a large bowl, combine the ground beef, ground pork, spinach, feta, breadcrumbs, egg, onion, garlic, 1 tsp oregano, and a pinch of salt and pepper. Mix gently with your hands until just combined.
Shape the mixture into a loaf and place it on one prepared baking sheet.
On the second baking sheet, toss the zucchini, bell pepper, eggplant, and cherry tomatoes with the olive oil, remaining 1 tsp oregano, salt, and pepper.
Bake both sheets for 45 minutes, or until the meatloaf reaches 160°F inside and the vegetables are tender.
Let the meatloaf rest for 5 minutes before slicing. Serve slices with the roasted vegetables on the side.