Heat the oven to 375°F. Line a rimmed baking sheet with parchment paper.
In a large bowl, combine the ground turkey, egg, breadcrumbs, onion, chipotle pepper, cumin, garlic powder, and salt. Mix gently until evenly combined, taking care not to pack the mixture too tightly.
Shape the mixture into a compact loaf on the prepared baking sheet. In a small bowl, stir together the tomato paste, honey, and half of the lime juice. Spread the glaze over the top and sides of the loaf.
Bake until the center reaches 165°F, about 45 to 55 minutes. Let the meatloaf rest for 10 minutes before slicing so it holds together.
While the meatloaf bakes, combine the corn, avocado, cilantro, and remaining lime juice in a bowl. Fold gently to keep the avocado pieces intact. Spoon the salsa over the sliced meatloaf just before serving.