Heat the oven to 375°F. Line a rimmed baking sheet with parchment paper.
In a large bowl, combine the ground turkey, egg, breadcrumbs, Monterey Jack, 2 tablespoons of the salsa, cumin, chili powder, garlic powder, and salt. Mix gently until evenly combined.
Shape the mixture into a compact loaf on the prepared baking sheet. Spread the remaining salsa over the top.
Bake until the center reaches 165°F on an instant-read thermometer, about 40 to 45 minutes. Let the meatloaf rest for 10 minutes before slicing.
While the meatloaf bakes, combine the black beans, corn, red bell pepper, red onion, lime juice, olive oil, and cilantro in a bowl. Toss gently and let the salad sit for a few minutes so the flavors can mingle.
Slice the meatloaf and serve with the black bean and corn salad.