Preheat the oven to 375 degrees and lightly grease a loaf pan.
In a large bowl, combine the ground beef, chorizo, breadcrumbs, egg, onion, garlic, cumin, chili powder, oregano, salt, and black pepper. Mix gently until the ingredients are evenly distributed.
Place half the meat mixture in the bottom of the prepared pan and press it into an even layer. Arrange the Pepper Jack strips down the center, keeping them in a single row.
Cover the cheese with the remaining meat mixture and press the edges to seal the cheese inside completely.
Bake for 50 to 60 minutes until the internal temperature reaches 160 degrees. Let the meatloaf rest for 10 minutes before slicing.
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Press the meat firmly around the cheese strips so none leaks out during baking. If the top browns too quickly, loosely cover the pan with foil for the last 15 minutes. Leftovers reheat well in a skillet over medium heat to keep the cheese from drying out.Course: Main Course
Cuisine: Mexican
Equipment: Mixing Bowl, Loaf Pan