In a large mixing bowl, combine the ground turkey, egg, breadcrumbs, onion, milk, garlic powder, salt, and black pepper. Mix gently until just combined, taking care not to compact the mixture.
Shape the turkey mixture into a compact loaf that will fit in your air fryer basket. Wrap the bacon slices around the loaf, slightly overlapping them, and tuck the ends underneath. Brush the top and sides with 2 tablespoons of the barbecue sauce.
Toss the sweet potato wedges with the olive oil and paprika. Arrange them in a single layer in the air fryer basket, leaving space in the center for the meatloaf. If your basket is too small, cook the wedges in a separate batch.
Set the bacon-wrapped meatloaf in the center of the basket. Air-fry at 350°F for 25 minutes. Brush the top with 2 tablespoons of barbecue sauce, then continue cooking for 10 to 15 minutes, until the center reaches 165°F and the bacon is browned. Check the wedges as they cook and remove any that are tender and browned before the meatloaf is done.
Transfer the meatloaf to a cutting board and let it rest for 5 minutes before slicing. Serve with the sweet potato wedges and the remaining barbecue sauce.